Human toxicology of chemical mixtures [electronic resource] : toxic consequences beyond the impact of one-component product and environmental exposures / Harold I. Zeliger.Material type: TextPublisher: Norwich, NY : William Andrew, c2008Description: 1 online resource (xxiii, 600 p.) : illISBN: 9780815515890; 0815515898; 9780815517948 (electronic bk.); 0815517947 (electronic bk.)Subject(s): Toxicological chemistry | Environmental toxicology | Environmental Illness | Environmental Exposure | Environmental Pollutants -- toxicity | Hazardous Substances -- toxicity | MEDICAL -- ToxicologyGenre/Form: Electronic books.Additional physical formats: Print version:: Human toxicology of chemical mixtures.DDC classification: 615.9/02 LOC classification: RA1219.3 | .Z45 2008ebOnline resources: ScienceDirect
This book considers how exposure to toxic mixtures affects the different physiological systems and organs, including the respiratory, cardiovascular, immunological, musculoskeletal, nervous and reproductive systems, as well as the various organs, including the kidneys, liver and skin. The author evaluates various sources of exposure, including air, water, and soil pollution; in utero exposure; chemicals contained in foods, cosmetics, and domestic cleaning products; adhesives and paints; industrial chemicals; pesticides; electromagnetic radiation; and chemicals ingested or inhaled during the use of alcohol, tobacco and narcotics. Human Toxicology of Chemical Mixtures also examines the interplay between exposure to these mixtures and the prevalence of various diseases and conditions, including autism, attention deficit hyperactivity disorder (ADHD), developmental neurotoxicology, multiple chemical sensitivity (MSC), chronic fatigue syndrome (CFS), fibromyalgia (FM), Gulf war syndrome, cancer and cancer clusters. The author also discusses how exposure to these mixtures yields the above diseases and conditions in different populations: fetuses, infants, pre-adolescent children, adolescents and adults. Finally, the book addresses the profound policy implications for formulation, labeling and use of chemical products, and it proposes more stringent exposure limits and warning requirements in light of the newly recognized toxic effects that are directly attributable to the mixture of toxic lipophilic and hydrophilic chemicals. * Addresses chemical mixtures, while most literature only deals with single chemicals exposure. * Explains why certain toxicological effects are observed. * Discusses diagnosis and treatment of injuries resulting from exposure. * Explores consequences of effects on product formulation, use, handling and required warnings. * Provides guidelines for safer development of personal care, cosmetic, industrial and consumer use products.
PART I Introduction to Chemical Toxicology of Mixtures -- Introduction -- Health Effects of Exposures to Chemical Mixtures -- Absorption of Chemical Mixtures -- Chemical Toxicology -- PART II Exposures to Chemical Mixtures -- Scope and sources of toxic exposures -- In Utero Exposure -- Air Pollution -- Water Pollution -- Soil Pollution -- Food -- Chemicals In and Around The Home -- Sick Building Syndrome -- Industrial Exposure -- Pesticides -- Alcohol and Tobacco: Recreational Toxins -- Electromagnetic Radiation and Toxic Exposure -- PART III Mixture Effects on Body Systems -- Respiratory System -- Nervous System -- Developmental Neurotoxicology -- Autism: Effect of Maternal Exposure to Neurotoxic Chemcials -- Attention Deficit Hyperactivity Disorder (ADHD) -- Endocrine System -- Toxic Infertility -- Teratogens -- Immune System -- Chemical Sensitivity: Multiple Chemical Sensitivity (MCS) -- Skin -- Musculoskeletal System -- Cardiovascular System -- Liver -- Kidneys -- Cancer -- Childhood Cancer -- Cancer Clusters -- PART IV REGULATORY REQUIREMENTS, CONCLUSIONS -- Regulatory Requirements -- Conclusions.
Includes bibliographical references and index.
Description based on print version record.