TY - BOOK AU - Hayat,M.A. TI - Molecular genetics, liver carcinoma and pancreatic carcinoma T2 - Handbook of Immunohistochemistry and in situ hybridization of human carcinomas SN - 9780120884049 AV - RC270.3.I46 I465 2004eb U1 - 616.994/0756 22 PY - 2004/// CY - Amsterdam, Boston PB - Elsevier Academic Press KW - Cancer KW - Immunodiagnosis KW - Immunohistochemistry KW - In situ hybridization KW - Fluorescence in situ hybridization KW - Liver KW - Genetic aspects KW - Pancreas KW - Neoplasms KW - diagnosis KW - Genetic Techniques KW - Situ Hybridization KW - methods KW - Electronic books N1 - Includes bibliographical references and index N2 - Immunohistochemistry is the use of specific antibodies to stain particular molecular species in situ. This technique has allowed the identification of many more cell types than could be visualized by classical histology, particularly in the immune system and among the scattered hormone-secreting cells of the endocrine system, and has the potential to improve diagnosis, prognosis and therapeutic options of cancer. This book discusses all aspects of immunohistochemistry and in situ hybridization technologies and the important role they play in reaching a cancer diagnosis. It provides step-by-step instructions on the methods of additional molecular technologies such as DNA microarrays, and microdissection, along with the benefits and limitations of each method. The topics of region-specific gene expression, its role in cancer development and the techniques that assist in the understanding of the molecular basis of disease are relevant and necessary in science today. * The only book available that translates molecular genetics into cancer diagnosis * The results of each Immunohistochemical and in situ hybridization method are presented in the form of color illustrations * Methods discussed were either developed or refined by expert contributors in their own laboratories UR - http://www.sciencedirect.com/science/book/9780120884049 ER -