BioMEMS and Biomedical Nanotechnology [electronic resource] : Volume I Biological and Biomedical Nanotechnology / edited by Mauro Ferrari, Abraham P. Lee, L. James Lee.Material type: TextLanguage: English Publisher: Boston, MA : Springer US, 2006Description: XXI, 520 p. online resourceContent type: text Media type: computer Carrier type: online resourceISBN: 9780387258423Subject(s): Engineering | Medicine | Biotechnology | Biomedical engineering | Nanotechnology | Engineering | Biomedical Engineering | Biophysics/Biomedical Physics | Nanotechnology | Biomedicine general | BiotechnologyAdditional physical formats: Printed edition:: No titleDDC classification: 610.28 LOC classification: R856-857Online resources: Click here to access online
Biomolecular Sensing for Cancer Diagnostics Using Carbon Nanotubes -- Microspheres for Drug Delivery -- Nanoscale Polymer Fabrication for Biomedical Applications -- 3D Micro- and Nanofabrication and Their Medical Application -- Sacrificial Oxide Layer for Drug Delivery -- Carbon Nanotube Biosensors -- Characterization Methods for Quality Control of Nanopore and Nanochannel Membranes -- Magnetic Nanoparticles for MR Imaging -- Polymer Design for Nonviral Gene Delivery -- Dip-Pen Technologies for Biomolecular Devices -- Engineered Inorganic-Binding Polypeptides for Bionanotechnology -- Dynamic Nanodevices Based on Protein Molecular Motors -- Nanodevices in Biomedical Applications -- Modeling Biomolecular Transport at the Nanoscale -- Nanotechnology in Cancer Drug Therapy: A Biocomputational Approach -- Nanomechanics and Tissue Pathology.
Less than twenty years ago photolithography and medicine were total strangers to one another. They had not yet met, and not even looking each other up in the classi?eds. And then, nucleic acid chips, micro?uidics and microarrays entered the scene, and rapidly these strangers became indispensable partners in biomedicine. Asrecentlyastenyearsagothenotionofapplyingnanotechnologytothe?ghtagainstd- ease was dominantly the province of the ?ction writers. Thoughts of nanoparticle-vehicled deliveryoftherapeuticalstodiseasedsiteswereanexerciseinscienti?csolitude,andgrounds for questioning one’s ability to think “like an established scientist”. And today we have nanoparticulate paclitaxel as the prime option against metastatic breast cancer, proteomic pro?lingdiagnostictoolsbasedontargetsurfacenanotexturing,nanoparticlecontrastagents for all radiological modalities, nanotechnologies embedded in high-distribution laboratory equipment, and no less than 152 novel nanomedical entities in the regulatory pipeline in the US alone. Thisisatransformingimpact,byanymeasure,withclearevidenceoffurtheracceleration, supported by very vigorous investments by the public and private sectors throughout the world. Even joining the dots in a most conservative, linear fashion, it is easy to envision scenarios of personalized medicine such as the following: patient-speci?c prevention supplanting gross, faceless intervention strategies; early detection protocols identifying signs of developing disease at the time when the disease is most easily subdued; personally tailored intervention strategies that are so routinely and inexpensively realized, that access to them can be secured by everyone; technologies allowing for long lives in the company of disease, as good neighbors, without impairment of the quality of life itself.