NMR spectroscopy and its application to biomedical research [electronic resource] / edited by Susanta K. Sarkar.

Contributor(s): Sarkar, Susanta KMaterial type: TextTextPublisher: Amsterdam ; New York : Elsevier, 1996Description: 1 online resource (xviii, 387 p.) : illISBN: 9780444894106; 0444894101; 9780080537597 (electronic bk.); 0080537596 (electronic bk.); 1281120073; 9781281120076Subject(s): Nuclear magnetic resonance spectroscopy | Biomolecules -- Analysis | Magnetic Resonance Spectroscopy | Molecular Biology -- methods | SCIENCE -- Life Sciences -- BiochemistryGenre/Form: Electronic books.Additional physical formats: Print version:: NMR spectroscopy and its application to biomedical research.DDC classification: 572/.33/028 LOC classification: QP519.9.N83 | N696 1996ebOnline resources: ScienceDirect
Contents:
Two-dimensional NMR spectroscopy : a graphical, "top-down" description / W.M. Westler -- Multidimensional NMR of macromolecules / L. Mueller and N. Vasant Kumar -- Preparation of p2sH, p13sC and p15sN isotopically-enriched proteins for NMR spectroscopic investigations / B.J. Stockman -- Protein structure determination from NMR data / P.L. Weber -- Protein dynamics as studied by solution NMR techniques / L.K. Nicholson, L.E. Kay and D.A. Torchia -- Nucleic acid structure and dynamics from NMR / D.E. Wemmer -- Carbohydrate structure and dynamics from NMR / L.E. Lerner -- Solid state NMR and its applications to biomedical research / A. Simmons, S.K. Sarkar and L.W. Jelinski.
Summary: NMR has become the most diverse spectroscopic tool available to date in biomedical research. It is now routinely used to study biomolecular structure and dynamics particularly as a result of recent developments of a cascade of highly sophisticated multidimensional NMR pulse sequences, and of advances in genetic engineering to produce biomolecules, uniformly or selectively enriched with <SUP>13</SUP>C, <SUP>15</SUP>N and <SUP>2</SUP>H. Features of this book: & bull; Provides an up-to-date treatment of NMR techniques and their application to problems of biomedical interest & bull; Most refined multidimensional pulse sequences including the basic aspects are covered by leading NMR spectroscopists. The book will be useful to NMR spectroscopists, biochemists, and to molecular biologists interested in the use of NMR techniques for solving biological problems.
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NMR has become the most diverse spectroscopic tool available to date in biomedical research. It is now routinely used to study biomolecular structure and dynamics particularly as a result of recent developments of a cascade of highly sophisticated multidimensional NMR pulse sequences, and of advances in genetic engineering to produce biomolecules, uniformly or selectively enriched with <SUP>13</SUP>C, <SUP>15</SUP>N and <SUP>2</SUP>H. Features of this book: & bull; Provides an up-to-date treatment of NMR techniques and their application to problems of biomedical interest & bull; Most refined multidimensional pulse sequences including the basic aspects are covered by leading NMR spectroscopists. The book will be useful to NMR spectroscopists, biochemists, and to molecular biologists interested in the use of NMR techniques for solving biological problems.

Includes bibliographical references and index.

Two-dimensional NMR spectroscopy : a graphical, "top-down" description / W.M. Westler -- Multidimensional NMR of macromolecules / L. Mueller and N. Vasant Kumar -- Preparation of p2sH, p13sC and p15sN isotopically-enriched proteins for NMR spectroscopic investigations / B.J. Stockman -- Protein structure determination from NMR data / P.L. Weber -- Protein dynamics as studied by solution NMR techniques / L.K. Nicholson, L.E. Kay and D.A. Torchia -- Nucleic acid structure and dynamics from NMR / D.E. Wemmer -- Carbohydrate structure and dynamics from NMR / L.E. Lerner -- Solid state NMR and its applications to biomedical research / A. Simmons, S.K. Sarkar and L.W. Jelinski.

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