Heparin-binding proteins [electronic resource] / H. Edward Conrad.Material type: TextPublisher: San Diego : Academic Press, c1998Description: 1 online resource (xx, 527 p.) : ill. (some col.)ISBN: 9780121860608; 0121860604; 9780080533902 (electronic bk.); 0080533906 (electronic bk.)Subject(s): Heparin | Protein binding | Heparan Sulfate Proteoglycan | Heparin | Proteoglycans | Proteins -- metabolism | Heparitin Sulfate | Heparinoids | MEDICAL -- Physiology | SCIENCE -- Life Sciences -- Human Anatomy & PhysiologyGenre/Form: Electronic books.Additional physical formats: Print version:: Heparin-binding proteins.DDC classification: 612.1/15 LOC classification: QP702.H4 | C66 1998ebOnline resources: ScienceDirect
This book describes the complex structures of heparins and heparan sulfates (heparinoids) and how they are generated by their biosynthetic pathways. The book also details the methodologies for studying these structures and their cellular metabolism. Heparin-Binding Proteins introduces the general nature of interactions between heparinoids and proteins, and presents the role for these structures in their interactions with the proteins of the hemostatic mechanisms, fibroblasts growth factors, superoxide dismutase, and lipoproteins. Key Features * Covers cellular metabolism of heparinoid proteoglycans * Written by a distinguished expert in the field of carbohydrate biochemistry * Describes the roles of heparan sulfate proteoglycans in * * Blood coagulation and fibrinolysis * Lipoprotein metabolism * Superoxide dismutase activity * Fibroblast growth factor responses of cells.
Preface. Conventions, Abbreviations, And Terminology. Heparin Vs. Heparan Sulfate. Structures of Heparinoids. Experimental Approaches for Determining Heparinoid Structures. Structural Modification of Heparinoids. The Cellular Metabolism of Heparan Sulfate. Interactions Between Heparinoids and Proteins. Antithrombin: The Prototype for Heparin-Binding Proteins. Heparin-Binding Proteins in Hemostasis. Fibroblast Growth Factors. Extracellular Superoxide Dismutase. Heparin-Binding Proteins in Lipoprotein Metabolism. Epilog. Appendix: Other Heparin-Binding Proteins. Subject Index.
Includes bibliographical references (p. 423-514) and index.
Description based on print version record.