Computational Methods in Systems Biology [electronic resource] : International Conference CMSB 2007, Edinburgh, Scotland, September 20-21, 2007. Proceedings / edited by Muffy Calder, Stephen Gilmore.

By: Calder, Muffy [editor.]Contributor(s): Gilmore, Stephen [editor.] | SpringerLink (Online service)Material type: TextTextLanguage: English Series: Lecture Notes in Computer Science: 4695Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg, 2007Description: X, 249 p. online resourceContent type: text Media type: computer Carrier type: online resourceISBN: 9783540751403Subject(s): Computer science | Software engineering | Database management | Computer simulation | Bioinformatics | Biology -- Data processing | Computer Science | Simulation and Modeling | Bioinformatics | Computer Appl. in Life Sciences | Software Engineering | Database Management | Computation by Abstract DevicesAdditional physical formats: Printed edition:: No titleDDC classification: 003.3 LOC classification: QA76.9.C65Online resources: Click here to access online
Contents:
Chemical Master Equation and Langevin Regimes for a Gene Transcription Model -- Simultaneous Stochastic Simulation of Multiple Perturbations in Biological Network Models -- Modelling Yeast Pre-rRNA Processing -- On the Analysis of Numerical Data Time Series in Temporal Logic -- Context Sensitivity in Logical Modeling with Time Delays -- Stochastic Simulation of Biological Systems with Dynamical Compartment Structure -- Computational Simulation of Optical Tracking of Cell Populations Using Quantum Dot Fluorophores -- A Formal and Integrated Framework to Simulate Evolution of Biological Pathways -- Reconstruction of Mammalian Cell Cycle Regulatory Network from Microarray Data Using Stochastic Logical Networks -- An Automated Translation from a Narrative Language for Biological Modelling into Process Algebra -- Expressive Models for Synaptic Plasticity -- Modelization and Simulation of Nano Devices in nano ? Calculus -- Efficient, Correct Simulation of Biological Processes in the Stochastic Pi-calculus -- A Unifying Framework for Modelling and Analysing Biochemical Pathways Using Petri Nets -- Reconstructing Metabolic Pathways by Bidirectional Chemical Search -- Decision Diagrams for the Representation and Analysis of Logical Models of Genetic Networks.
In: Springer eBooksSummary: Systems biology is an exciting new ?eld bringing together life scientists, mat- maticians,computer scientists and engineersto explorea new and deeper und- standing of biological systems. Computational models and methods of analysis are essential components of the systems biology programme, not only re?ecting, but also driving wet lab experimentation and the formation of new hypotheses about system behaviour. This volumecontains theproceedingsofthe?fth meeting oftheinternational conference on Computational Methods in Systems Biology. The ?rst conference was in Trento, Italy in 2003. The second meeting was in Paris in 2004, and in 2005 the conference came to Edinburgh for the ?rst time. Last year’s meeting was again in Trento and this year the conference was again in Edinburgh. This year the conference attracted over 60 paper submissions. Sixteen of these were selected for presentation at the conference. In choosing the 16 best papers, the conference Chairs received wonderful support from the Programme Committee,who deliveredthoroughandinsightful reviewsofallpapersina very short time scale. We thank all of the members of the Programme Committee and their sub-referees for their industriousness. We also thank the authors for responding swiftly to the comments of the referees and revising their papers to address these comments earnestly. The electronic submission of papers, refereeing and Programme Committee workweremadepossiblebytheexcellentEasyChairfreeconferencemanagement system.EasyChairmanagedalloftheaspectsofthereviewprocessfromsubm- sion to review and discussion, through to sending decisionsby e-mailto authors. EasyChair compiled the list of referees which appears in this front matter. We give hearty thanks to Andrei Voronkov for providing this wonderful service to the scienti?c community.
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Chemical Master Equation and Langevin Regimes for a Gene Transcription Model -- Simultaneous Stochastic Simulation of Multiple Perturbations in Biological Network Models -- Modelling Yeast Pre-rRNA Processing -- On the Analysis of Numerical Data Time Series in Temporal Logic -- Context Sensitivity in Logical Modeling with Time Delays -- Stochastic Simulation of Biological Systems with Dynamical Compartment Structure -- Computational Simulation of Optical Tracking of Cell Populations Using Quantum Dot Fluorophores -- A Formal and Integrated Framework to Simulate Evolution of Biological Pathways -- Reconstruction of Mammalian Cell Cycle Regulatory Network from Microarray Data Using Stochastic Logical Networks -- An Automated Translation from a Narrative Language for Biological Modelling into Process Algebra -- Expressive Models for Synaptic Plasticity -- Modelization and Simulation of Nano Devices in nano ? Calculus -- Efficient, Correct Simulation of Biological Processes in the Stochastic Pi-calculus -- A Unifying Framework for Modelling and Analysing Biochemical Pathways Using Petri Nets -- Reconstructing Metabolic Pathways by Bidirectional Chemical Search -- Decision Diagrams for the Representation and Analysis of Logical Models of Genetic Networks.

Systems biology is an exciting new ?eld bringing together life scientists, mat- maticians,computer scientists and engineersto explorea new and deeper und- standing of biological systems. Computational models and methods of analysis are essential components of the systems biology programme, not only re?ecting, but also driving wet lab experimentation and the formation of new hypotheses about system behaviour. This volumecontains theproceedingsofthe?fth meeting oftheinternational conference on Computational Methods in Systems Biology. The ?rst conference was in Trento, Italy in 2003. The second meeting was in Paris in 2004, and in 2005 the conference came to Edinburgh for the ?rst time. Last year’s meeting was again in Trento and this year the conference was again in Edinburgh. This year the conference attracted over 60 paper submissions. Sixteen of these were selected for presentation at the conference. In choosing the 16 best papers, the conference Chairs received wonderful support from the Programme Committee,who deliveredthoroughandinsightful reviewsofallpapersina very short time scale. We thank all of the members of the Programme Committee and their sub-referees for their industriousness. We also thank the authors for responding swiftly to the comments of the referees and revising their papers to address these comments earnestly. The electronic submission of papers, refereeing and Programme Committee workweremadepossiblebytheexcellentEasyChairfreeconferencemanagement system.EasyChairmanagedalloftheaspectsofthereviewprocessfromsubm- sion to review and discussion, through to sending decisionsby e-mailto authors. EasyChair compiled the list of referees which appears in this front matter. We give hearty thanks to Andrei Voronkov for providing this wonderful service to the scienti?c community.

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