Guide to human genome computing [electronic resource] / edited by Martin J. Bishop. - 2nd ed. - San Diego, Calif. : Academic Press, 1998. - 1 online resource (xiv, 306 p.) : ill.

Includes bibliographical references and index.

L. Stein, Introduction to Human Genome Computing via the World Wide Web. -- M. Rhodes and R. Elaswarapu, Biological Materials and Services. -- S. Bryant, Managing Pedigree and Genotype Data. -- P. Sham and J. Zhao, Linkage Analysis Using Affected Sib-Pairs. -- M. Bishop, Comparative Mapping in Man and Vertebrates. -- L. McCarthy and C. Soderland, Radiation Hybrid Mapping. -- C. Soderland, S. Gregory, and I. Dunham, Sequence Ready Clone Maps. -- S. Dear, Software for Human Genome Sequencing. -- G. Slater, Human EST Sequences. -- L. Milanesi and I. Rogozin, Prediction of Human Gene Structure. -- A. Krogh, Gene Finding: Putting the Parts Together. -- D. Davidson and C. Dubreuil, Gene Expression Databases. Introduction to human genome computing via the world wide web / Biological materials and services / Managing pedigree and genotype data / Linkage analysis using affected sib-pairs / Comparative mapping in humans and vertebrates / Martin Bishop -- Radiation hybrid mapping / Sequence ready clone maps / Software for human genome sequencing / Human EST sequences / Prediction of human gene structure / Gene finding : putting the parts together / Gene-expression databases / Lincoln D. Stein -- Michael Rhodes, Ramnath Elaswarapu -- Stephen P. Bryant -- Pak Sham, Jinghua Zhao -- Linda McCarthy, Carol Soderlund -- Carol Soderlund, Simon Gregory, Ian Dunham -- Simon Dear -- Guy St C. Slater -- Luciano Milanesi, Igor B. Rogozin -- Anders Krogh -- Duncan Davidson, Martin Ringwald, Christophe Dubreuil.

The Guide to Human Genome Computing is invaluable to scientists who wish to make use of the powerful computing tools now available to assist them in the field of human genome analysis. This book clearly explains access and use of sequence databases, and presents the various computer packages used to analyze DNA sequences, measure linkage analysis, compare and align DNA sequences from different genes or organisms, and infer structural and functional information about proteins from sequence data. This Second Edition contains completely updated material. Rather than a revision of the previous volume, the Second Edition is essentially a new book, based on the subjects which will be of interest over the coming years. This new book is international, both in scope and authorship. Computing resources for the following are clearly explained: * Internet resources - databases etc. * Genetic analysis * Sib-pair studies * Comparative mapping * Radiation hybrids * Sequence ready clone maps * Human genome sequencing * ESTs * Gene prediction * Gene expression.

9780121020514 0121020517

80286:80286 Elsevier Science & Technology http://www.sciencedirect.com


Human gene mapping--Data processing.
Human gene mapping--Computer network resources.
Nucleotide sequence--Data processing.
Nucleotide sequence--Computer network resources.
Genome, Human.
Chromosome Mapping--methods.
Sequence Analysis.
Medical Informatics Computing.
Nucelotide sequence--Computer network resources.
Cartes chromosomiques humaines--Informatique.
Cartes chromosomiques humaines--Information �electronique.
G�enome humain--S�equen�cage--Informatique.
G�enome humain--S�equen�cage--Information �electronique.
G�enome humain--Informatique.
Cartes chromosomiques humaines--Ressources Internet.


Electronic books.

QH445.2 / .G85 1998eb

611/.01816

1998 E-945 QH 447 / G946 1998


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